The road to personalized myeloma medicine: Patient-specific single-domain antibodies for anti-idiotypic radionuclide therapy

Autorzy:

Janik Puttemans, Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel,

Benoit Stijlemans, Department of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Myeloid Cell Immunology Lab, VIB Center for Inflammation Research,

Marleen Keyaerts, Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel, Nuclear Medicine Department, UZ Brussel,

Sam Vander Meeren, Department of Clinical Biology, Hematology Division, UZ Brussel,

Wim Renmans, Department of Clinical Biology, Hematology Division, UZ Brussel,

Karel Fostier, Department of Hematology, OLV Aalst, Department of Hematology, UZ Brussel,

Pieterjan Debie, Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel,

Heleen Hanssens, Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel,

Magdalena Rodak, Institute of Nuclear Chemistry and Technology, uczestniczka projektu RadFarm

Marek Pruszynski, Institute of Nuclear Chemistry and Technology, Faculty of Chemistry, University of Warsaw,

Kim De Veirman, Department of Hematology and Immunology, Vrije Universiteit Brussel,

Karin Vanderkerken, Department of Hematology and Immunology, Vrije Universiteit Brussel,

Tony Lahoutte, Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel, Nuclear Medicine Department, UZ Brussel,

Alfred Morgenstern, European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security,

Frank Bruchertseifer, European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security,

Nick Devoogdt, Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel,

Matthias D'Huyvetter Department of Medical Imaging, Laboratory for In Vivo Cellular and Molecular Imaging, Vrije Universiteit Brussel

Finansowanie:

This study was supported by grant funding from the Stichting Tegen Kanker (Translational & Clinical Research Grant 1635, 2016), and travel, infrastructure and research funding from Research Foundation-Flanders (FWO) (G028220N, I001618N and VS02919N). J.P. and H.H. received a personal predoctoral mandate from FWO. M.D. and K.D.V. are postdoctoral fellows of FWO, and T.L. and M.K. are senior clinical investigators of FWO. M.R. was funded by Operational Project Knowledge Education Development, co-financed by the European Social Fund (POWR.03.02.00-00-I009/17-00).

Rok wydania:
2021

Liczba tomów:
1

Liczba stron:
28